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Discovering Key Applications for Ussing Chambers

The Ussing chamber is a classic experimental apparatus used to study the transport properties and barrier functions of epithelial tissues—surfaces that line organs such as the intestines, lungs, and kidneys. By mounting a section of live tissue between two chambers, researchers can precisely control the environment on both the “mucosal” (luminal) side and the “serosal”…

Carvacrol’s Protective Efficacy Against DSS-Induced Colitis: A Comprehensive Summary

Discover how carvacrol combats DSS-induced colitis by downregulating NF-κB/MAPK signaling, boosting TGR5 expression, and reinforcing gut barrier integrity for potential therapeutic benefits – L-Cysteine protects intestinal integrity, attenuates intestinal inflammation and oxidant stress, and modulates NF-κB and Nrf2 pathways in weaned piglets after LPS challenge. Read the full article here: https://journals.sagepub.com/doi/full/10.1177/1753425916632303 This study investigates the protective…

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Exploring Neural Regulation of Intestinal Ion Transport: Insights from EasyMount Ussing Chamber Experiments

In the study “Neural influences on human intestinal epithelium in vitro,” researchers actively investigated how multiple neural factors importantly affect ion transport across human intestinal epithelial tissues. To achieve this goal, they actively used the EasyMount Ussing Chamber system from Physiologic Instruments, which effectively enabled them to mount isolated intestinal tissue samples between two chambers,…

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Unveiling Gut Dynamics: How the EasyMount Ussing Chamber Advanced Intestinal Transport Research

Researchers in the study titled “Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine” used the EasyMount Ussing Chamber system from Physiologic Instruments. They sought to examine multiple dietary components and their effects on ion transport across the intestinal mucosa. The team used this apparatus to mount isolated…

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Exploring Flavonoid Effects on Respiratory Epithelium: Insights Using the EasyMount Ussing Chamber

In the study “Modulation of the Respiratory Epithelium Physiology by Flavonoids—Insights from 16HBEσ Cell Model,” researchers actively examined how specific flavonoids—kaempferol, luteolin, as well as naringenin—effect the physiology of human bronchial epithelial cells. Researchers sought to understand how these compounds importantly influence multiple aspects of cell behavior. They concentrated on cell metabolic activity, proliferation, epithelial…